Pair Name	All-trans retinoic acid, Anti-PD-L1 antibody
Disease Info	[ICD-11: 2C77]	Cervical cancer		Investigative
Gene Regulation	Down-regulation	Expression	ARG1	hsa383
	Down-regulation	Expression	CD274	hsa29126
	Down-regulation	Expression	CYBB	hsa1536
	Up-regulation	Expression	IFNG	hsa3458
	Down-regulation	Expression	NOS2	hsa4843
	Up-regulation	Expression	TNF	hsa7124
In Vitro Model	HeLa	Human papillomavirus-related cervical adenocarcinoma	Homo sapiens (Human)	CVCL_0030
	C-33 A	Human papillomavirus-independent cervical squamous cell carcinoma	Homo sapiens (Human)	CVCL_1094
	U14	Cervical carcinoma	Mus musculus (Mouse)	CVCL_9U56
In Vivo Model	Mouse cervical cancer U14 cells were prepared as mentioned above and a total of 1×10⁶ U14 cells were subcutaneously injected into the abdominal cavity of the mice for a week.
Result	Inhibition of myeloid-derived suppressive cell function with all-trans retinoic acid enhanced anti-PD-L1 efficacy in cervical cancer.